Learn about the latest developments and evidence-based approaches in antiplatelet therapy through a comprehensive medical lecture delivered by Dr. René Boudreau, a PGY6 Cardiology Resident at the University of Ottawa Heart Institute. Explore nearly five decades of evidence from 1974-2021, including pivotal studies like TRITON-38 and PRECISE-DAPT. Examine the evolution of dual antiplatelet therapy (DAPT) guidelines, focusing on complex PCI cases, risk stratification using the DAPT Score, and management strategies for both high and non-high bleeding risk patients. Gain practical insights into treating established coronary artery disease (CAD) and understand the latest ESC 2020 guidelines for both short and prolonged DAPT protocols.