Learn essential system design concepts for scaling applications to handle global traffic in this comprehensive technical video. Master the progression from single-server deployments to multi-region architectures, exploring key concepts like data center organization, regional deployment strategies, and geolocation routing. Understand the intricacies of request flow management, multi-master database implementations, and effective caching strategies. Examine both advantages and challenges of multi-region deployments, discover techniques for implementing global failover mechanisms, and leverage Content Delivery Networks (CDNs) for optimal performance. Through detailed examples and practical scenarios, gain the knowledge needed to architect robust, scalable systems capable of serving users worldwide.