Explore the complexities of immunotherapy in oncology through this 53-minute physician grand rounds presentation. Delve into an overview of therapeutics, drug nomenclature, and immune checkpoint treatments. Examine immune-related adverse events, the role of gut microbiome, and COVID-19 side effects. Learn about CTLA antibody drugs, infusion reactions, and thyroid management. Understand guidelines for managing primary adrenal insufficiency and NCCN recommendations. Analyze a case study, discuss steroid and antibiotic use, and explore myocarditis. Gain insights on predicting side effects, monitoring parameters, and key takeaway messages for effective immunotherapy management in cancer treatment.