Explore the groundbreaking discoveries of mass independent isotope effects in the solar system through this 26-minute conference talk presented at the Mineralogical Society of America's Short Course on Triple Oxygen Isotope Geochemistry. Delve into the past, present, and future of this field as authors Mark Thiemens and Mang Lin discuss key topics including measurements, photochemistry, carbon monoxide, meteorites, shielding models, secondary effects, water safety, solar wind, and symmetry-dependent effects. Gain insights into single-stage fractionation factors, correction factors, and the bottom line of these findings. Engage with the presentation's comprehensive syllabus, covering everything from introductory concepts to specific tests and models, concluding with a question-and-answer session.