How cancer-associated fibroblasts promote T-cell exclusion in human lung tumors...
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Explore a 24-minute lecture from the Fields Institute's Mathematical Oncology program where Professor Martine Ben Amar from Ecole Normale Supérieure and UPMC examines the physical mechanisms behind how cancer-associated fibroblasts prevent T-cells from reaching lung tumors. Delve into the intersection of computational fluid dynamics, mechanics, and biology to understand the complex interactions between cancer cells and immune responses in the tumor microenvironment. Learn about cutting-edge research that combines mathematical modeling with oncology to better comprehend T-cell exclusion patterns and their implications for cancer treatment strategies.
How Cancer-Associated Fibroblasts Promote T-Cell Exclusion in Human Lung Tumors: A Physical Perspective