Save Big on Coursera Plus. 7,000+ courses at $160 off. Limited Time Only! Grab it Watch a 42-minute research lecture from the Inaugural Brain Resilience Symposium exploring lysosome function and its critical role in brain health and disease. Delve into groundbreaking research on subcellular metabolism and organelle dysfunction, with particular focus on Batten disease and CLN3 deficiency. Learn about the accumulation of Glycerophosphodiesters in lysosomes, the essential role of choline in brain homeostasis, and discover a novel lysosomal phospholipid salvage pathway. Examine findings from endolysosomal CRISPR-Cas9 screening that identifies crucial lysosomal proteins, and understand the implications of SPNS1 deficiency on lysophospholipid transport. Presented by Monther Abu-Remaileh, this talk provides deep insights into the optimization of subcellular biochemistry and its potential impact on treating various human diseases.