Explore the intricacies of building large-scale Node.js applications in this 30-minute conference talk from Amsterdam JSNation 2019. Delve into architectural patterns, layers, and common misunderstandings in Node.js development. Learn how to move beyond "hello world" examples and construct robust, scalable applications. Discover the impact of GraphQL on application architecture and gain insights into the limitations of popular JavaScript frameworks. Acquire valuable knowledge to enhance your Node.js development skills and create more efficient, maintainable applications.