Explore the capabilities of GraalVM, a high-performance polyglot virtual machine, in this comprehensive conference talk. Dive deep into GraalVM's applications for Java and JavaScript developers, learning how to optimize peak performance, create native images for instant startup, and seamlessly integrate multiple programming languages. Discover techniques for understanding JIT compiler behavior, collecting debug information for profiling, and overcoming limitations in native images. Examine polyglot applications and their impact on code writing, mastering the polyglot API for effective language mixing. Gain hands-on experience through a series of demos and explore common tooling like VisualVM and Chrome debugger for GraalVM-supported languages. Apply the insights gained directly to your development projects and enhance your programming skills across Java, JavaScript, Python, Ruby, and more.