Explore advanced techniques for exploiting HTTP request isolation vulnerabilities in this Black Hat conference talk. Delve into HTTP desynchronization attacks that allow remote, unauthenticated attackers to manipulate web infrastructure, compromise visitor security, and exploit system weaknesses. Learn about the HTTP chain, desynchronization methods, detection strategies, and real-world case studies involving backend systems, cache poisoning, and CDNs. Examine specific examples, including attacks on PayPal's infrastructure, and witness a live demonstration. Gain insights into the underlying mechanisms of these attacks, their potential impact, and effective mitigation strategies to protect web applications from HTTP desync vulnerabilities.