Explore the critical issue of antibiotic-resistant bacteria in this compelling lecture from the American Society for Microbiology. Delve into the 2011 outbreak of carbapenem-resistant Klebsiella pneumoniae at the NIH Clinical Center, a pathogen topping the CDC's list of urgent threats. Learn how Dr. Julie Segre, a senior investigator at the National Human Genome Research Institute, utilized cutting-edge DNA sequencing to trace the outbreak's origin and spread. Gain insights into the growing global challenge of antibiotic-resistant infections, particularly in hospital settings. Discover the importance of infection control measures, including hand hygiene and contact isolation. Examine the role of next-generation sequencing in combating these dangerous pathogens and the challenges of implementing patient-specific sequencing. Understand the significance of hospital surveillance programs in detecting and managing antibiotic-resistant bacteria. This Elizabeth O. King Lecture offers a comprehensive look at the intersection of genomics, microbiology, and public health in addressing one of the most pressing medical challenges of our time. Read more