Explore the complexities of reconciling genotypic and phenotypic susceptibility tests in this 41-minute American Society for Microbiology podcast. Delve into the advantages and challenges of both testing methods, understand why discrepancies occur, and learn how clinical microbiologists should handle conflicting results. Gain insights from experts Dr. Patricia Simner and Dr. Jennifer Dien Bard on comparing test accuracies, interpreting results for gram-negative organisms, and collaborating with other healthcare teams. Discover recommendations for implementing and interpreting genotypic and phenotypic testing in clinical microbiology laboratories to improve patient care and antimicrobial stewardship.