Explore the critical issue of antibiotic scarcity in this 44-minute conversation featuring experts Dr. Helen Boucher and Dr. Karen Bush. Delve into the reasons behind the declining antibiotic development pipeline, examine new initiatives aimed at revitalizing the antibiotic market, and discover strategies to boost antibiotic development. Learn about the challenges facing pharmaceutical companies, the potential of betalactamase inhibitors, and the impact of regulatory environments on drug development. Gain insights into the AMR Action Fund, nonprofit approaches, and proposed incentives to stimulate antibiotic research. Understand the complexities of clinical trials, patient recruitment issues, and the evolving landscape of antimicrobial resistance. Conclude with expert predictions and final thoughts on addressing this global health concern.