Explore the world of total laboratory automation in clinical microbiology through this informative 47-minute video from the American Society for Microbiology. Gain insights into the definition, benefits, and implementation of automated systems in microbiology labs. Learn about the impact on lab staff, caregivers, and patients, as well as the resources required for conversion. Discover how automation affects specimen collection, workflow, and the recovery of fastidious organisms. Understand the challenges, including training requirements and potential downtime. Delve into the physical changes needed in labs, the role of increased technologists, and the potential of machine learning in this evolving field. Engage with editors in conversation as they address key questions and discuss the future of clinical microbiology automation.