Explore a comprehensive lecture on emerging microbial threats at the intersection of human, animal, and ecosystem health. Delve into the factors contributing to disease emergence, examine real-world examples, and learn about current efforts to address these challenges. Gain insights from James Hughes, MD, Professor of Medicine at Emory University School of Medicine, as he discusses the complexities faced by microbiologists, physicians, veterinarians, and public health professionals in combating emerging infections. Discover the impact of global trends such as urbanization, international travel, microbial adaptation, and social inequality on disease transmission. Examine the stages of cross-species transmission, prediction considerations, and opportunities for prevention, detection, and response to zoonotic diseases. Enhance your understanding of public health surveillance and the importance of a multidisciplinary approach in addressing emerging microbial threats.