Explore a 20-minute conference talk from the ACM CHI Conference on Human Factors in Computing Systems that delves into the challenges and solutions for implementing telemedicine in low-resource environments. Discover how researchers Rajesh Chandwani and Neha Kumar investigate a long-standing telemedicine program in Lucknow, India, using the lenses of human infrastructure and seamful spaces. Learn about three critical aspects for successful telemedicine implementation: conceptualizing telemedicine as connected nodes, identifying and engaging local doctors as 'carrying agents,' and ensuring patient co-creation. Gain insights into how recognizing and addressing the seams between central and peripheral infrastructures can lead to more effective telemedicine programs in resource-constrained settings.