Cells express the genes they need at the right quantities
5
A gene expression profile is the calling card of a cell
6
Knowing our cells is essential to understand the genes that cause disease
7
Gene expression: coordinates for a map of all human cells
8
Test case: the airways
9
Test case: Zebrafish development
10
A cell tree for zebrafish embryogenesis
11
Tracing blood formation in humans
12
Algorithms allow us to "play back the tape"
13
Immunotherapies are the most important therapeutic advance in cancer care, but...
14
New proposed option for combination treatment
15
Test case: Inflammatory bowel disease
16
A single cell atlas of the colon of healthy and UC patients
17
A map across multiple diseases
18
Human Cell Atlas: Mission
19
HCA principles and values
20
Large scale, international funding for data collection, method development, and data platform
21
Phase 1: the first draft
Description:
Explore the groundbreaking Human Cell Atlas project in this 50-minute Aspen Lecture. Delve into the ambitious effort to create a comprehensive, searchable map of human cells, akin to a "Google map for the human body." Learn about the project's potential to revolutionize personalized medicine by cataloging cellular subtypes, gene expression profiles, and environmental influences. Discover how this atlas is being applied to various test cases, including airway studies, zebrafish development, and human blood formation. Gain insights into the project's impact on cancer immunotherapies and inflammatory bowel disease research. Understand the mission, principles, and international scope of the Human Cell Atlas initiative, including its large-scale funding and phased approach to data collection and platform development.