Explore the complexities of medical innovation in this 15-minute TED talk, where doctor and biomedical entrepreneur Elazer Edelman challenges the assumption that more knowledge automatically leads to better innovation. Discover the hidden risks in this belief and learn about the importance of bridging gaps between disciplines. Delve into topics such as the science of myocardial infarction, device biology paradoxes, and computational modeling for improved medical devices. Examine the concept of changing device design to optimize biology and consider the benefits of multidisciplinary thinking over siloed expertise. Reflect on the mass-velocity paradox in medical advancement and understand the moral obligation scientists face in connecting diverse fields of knowledge to drive meaningful progress in healthcare.