Explore groundbreaking research in quantum physics through a Nobel Prize lecture delivered by Serge Haroche at the APS March Meeting 2013. Delve into the fascinating world of controlling photons in a box and investigating the boundary between quantum and classical physics. Learn about thought experiments, the development of cavity quantum electrodynamics (QED), and the creation of a "photon box" for counting individual light particles. Discover the journey from early laser and microwave experiments to cutting-edge quantum research, including insights into practical quantum computing and outstanding questions in the field. Gain valuable knowledge from a renowned physicist as he shares his experiences, acknowledges collaborators, and addresses audience inquiries in this comprehensive 51-minute talk.