Explore the evolution of global challenges like poverty, inequality, climate change, and depression in this thought-provoking conference talk from the SingularityU Peru Summit. Join Nathaniel Calhoun, Vice Chair Global Grand Challenge Faculty at Singularity University, as he examines worsening global problems that could destabilize Peru and the region. Delve into topics such as global inequality, mental health, public health interventions, planetary boundaries, hunger, displacement, urbanization, and wars. Investigate the law of amplification, the role of government and new business structures, and the impact of technology on civil liberties. Question where the technology to combat these challenges is and how it can be effectively utilized. Gain insights into potential solutions and the importance of principled ideas in addressing these complex issues.