Explore the intricate relationship between Istio and DNS in this 23-minute conference talk by Costin Manolache from Google. Delve into Istio's dependence on DNS for secure IP generation and name resolution outside local clusters, as well as its ability to intercept and generate responses. Examine the modern capabilities of DNS, including TLS and HTTP support, signing mechanisms, and rich information provision beyond IP addresses. Gain insights into the various integration options between Istio and DNS, with a particular focus on security considerations and mixed execution environments. Enhance your understanding of these critical components in cloud native computing and their impact on service mesh architecture.